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1

Treatment of restless legs syndrome: Evidence-based review and implications for clinical practice (Revised 2017) §

Winkelmann, Juliane, Allen, Richard P., Högl, Birgit, Inoue, Yuichi, Oertel, Wolfgang, Salminen, Aaro V., Winkelman, John W., Trenkwalder, Claudia, Sampaio, Cristina

Journal:

Movement Disorders

Year:

2018

Language:

english

File:

PDF, 375 KB

english, 2018

2

Restless Legs Syndrome and Other Movement Disorders of Sleep—Treatment Update

Salminen, Aaro V., Winkelmann, Juliane

Journal:

Current Treatment Options in Neurology

Year:

2018

Language:

english

File:

PDF, 1024 KB

english, 2018

3

Prolonged release oxycodone–naloxone for treatment of severe restless legs syndrome after failure of previous treatment: a double-blind, randomised, placebo-controlled trial with an open-label extension

Trenkwalder, Claudia, Beneš, Heike, Grote, Ludger, García-Borreguero, Diego, Högl, Birgit, Hopp, Michael, Bosse, Björn, Oksche, Alexander, Reimer, Karen, Winkelmann, Juliane, Allen, Richard P, Kohnen,

Journal:

The Lancet Neurology

Year:

2013

Language:

english

File:

PDF, 239 KB

english, 2013

4

Genetik in Neurologie und Psychiatrie; Genetics in neurology and psychiatry;

Rietschel, Marcella, Winkelmann, Juliane

Journal:

Year:

2019

Language:

german

File:

PDF, 320 KB

german, 2019

5

Genetics of restless legs syndrome (RLS): State-of-the-art and future directions

Juliane Winkelmann, Oli Polo, Federica Provini, Sonja Nevsimalova, David Kemlink, Karel Sonka, Birgit Högl, Werner Poewe, Karin Stiasny-Kolster, Wolfgang Oertel, Al de Weerd, Luigi Ferini Strambi, Mar

Journal:

Movement Disorders

Year:

2007

Language:

english

File:

PDF, 95 KB

english, 2007

6

When Parkinson’s disease patients go to sleep: specific sleep disturbances related to Parkinson’s disease

Eva C. Schulte, Juliane Winkelmann

Journal:

Journal of Neurology

Year:

2011

Language:

english

File:

PDF, 201 KB

english, 2011

7

Structural brain correlates of heart rate variability in a healthy young adult population

Winkelmann, Tobias, Thayer, Julian F., Pohlack, Sebastian, Nees, Frauke, Grimm, Oliver, Flor, Herta

Journal:

Brain Structure and Function (Anatomy and Embryology 1891-2006)

Year:

2017

Language:

english

File:

PDF, 896 KB

english, 2017

8

Clinical Characteristics and Frequency of the Hereditary Restless Legs Syndrome in a Population of 300 Patients

Winkelmann, Juliane, Wetter, Thomas C., Collado-Seidel, Victor, Gasser, Thomas, Dichgans, Martin, Yassouridis, Alexander, Trenkwalder, Claudia

Journal:

Year:

2000

Language:

english

File:

PDF, 33 KB

english, 2000

9

Exomdiagnostik in der Neurologie; Exome diagnostics in neurology;

Zech, Michael, Wagner, Matias, Schormair, Barbara, Oexle, Konrad, Winkelmann, Juliane

Journal:

Year:

2019

Language:

german

File:

PDF, 488 KB

german, 2019

10

Magnetic resonance imaging findings in corticobasal degeneration

Juliane Winkelmann, Dorothee P. Auer, Christian Lechner, Gregor Elbel, Claudia Trenkwalder

Journal:

Movement Disorders

Year:

1999

Language:

english

File:

PDF, 253 KB

english, 1999

11

Periodic limb movements in syringomyelia and syringobulbia

Juliane Winkelmann, Thomas C. Wetter, Claudia Trenkwalder, Dorothee P. Auer

Journal:

Movement Disorders

Year:

2000

Language:

english

File:

PDF, 86 KB

english, 2000

12

Complex segregation analysis of restless legs syndrome provides evidence for an autosomal dominant mode of inheritance in early age at onset families

Juliane Winkelmann, Bertram Muller-Myhsok, Hans-Ulrich Wittchen, Bettina Hock, Muriel Prager, Hildegard Pfister, Andreas Strohle, Ilonka Eisensehr, Martin Dichgans, Thomas Gasser, Claudia Trenkwalder

Journal:

Annals of Neurology

Year:

2002

Language:

english

File:

PDF, 97 KB

english, 2002

13

Long-term course of restless legs syndrome in dialysis patients after kidney transplantation

Juliane Winkelmann, Anette Stautner, Walter Samtleben, Claudia Trenkwalder

Journal:

Movement Disorders

Year:

2002

Language:

english

File:

PDF, 61 KB

english, 2002

14

Long-Term follow-up on restless legs syndrome patients treated with opioids

Arthur S. Walters, Juliane Winkelmann, Claudia Trenkwalder, June M. Fry, Vandana Kataria, Mary Wagner, Rakesh Sharma, Wayne Hening, Liren Li

Journal:

Movement Disorders

Year:

2001

Language:

english

File:

PDF, 41 KB

english, 2001

15

Evidence for further genetic locus heterogeneity and confirmation of RLS-1 in restless legs syndrome

Juliane Winkelmann, Peter Lichtner, Benno Pütz, Claudia Trenkwalder, Stephanie Hauk, Thomas Meitinger, Tim Strom, Bertram Muller-Myhsok

Journal:

Movement Disorders

Year:

2006

Language:

english

File:

PDF, 191 KB

english, 2006

16

Augmentation as a treatment complication of restless legs syndrome: Concept and management

Diego García-Borreguero, Richard P. Allen, Heike Benes, Christopher Earley, Svenja Happe, Birgit Högl, Ralf Kohnen, Walter Paulus, David Rye, Juliane Winkelmann

Journal:

Movement Disorders

Year:

2007

Language:

english

File:

PDF, 184 KB

english, 2007

17

Animal studies in restless legs syndrome

Paul Christian Baier, William G. Ondo, Juliane Winkelmann

Journal:

Movement Disorders

Year:

2007

Language:

english

File:

PDF, 73 KB

english, 2007

18

Variants in the neuronal nitric oxide synthase (nNOS, NOS1) gene are associated with restless legs syndrome

Juliane Winkelmann, Peter Lichtner, Barbara Schormair, Manfred Uhr, Stephanie Hauk, Karin Stiasny-Kolster, Claudia Trenkwalder, Walter Paulus, Ines Peglau, Ilonka Eisensehr, Thomas Illig, H.-Erich Wic

Journal:

Movement Disorders

Year:

2008

Language:

english

File:

PDF, 277 KB

english, 2008

19

Short-term attention and verbal fluency is decreased in restless legs syndrome patients

Stephany Fulda, Marie E. Beitinger, Simone Reppermund, Juliane Winkelmann, Thomas C. Wetter

Journal:

Movement Disorders

Year:

2010

Language:

english

File:

PDF, 130 KB

english, 2010

20

Myoclonus-dystonia in 18p deletion syndrome

Markus C. Kowarik, Sabine Langer, Corinna Keri, Bernhard Hemmer, Konrad Oexle, Juliane Winkelmann

Journal:

Movement Disorders

Year:

2011

Language:

english

File:

PDF, 273 KB

english, 2011

21

Treatment of restless leg syndrome with pergolide—an open clinical trial

Juliane Winkelmann, Thomas C. Wetter, Karen Stiasny, Wolfgang H. Oertel, Claudia Trenkwalder

Journal:

Movement Disorders

Year:

1998

Language:

english

File:

PDF, 331 KB

english, 1998

22

The restless legs syndrome—A genetic view of the disease

Juliane Winkelmann, Karin Eckard, Bertram Müller-Myshok, Thomas Gasser, Claudia Trenkwalder

Journal:

Somnologie - Schlafforschung und Schlafmedizin

Year:

2002

Language:

english

File:

PDF, 58 KB

english, 2002

23

Expression of matrix metalloproteinases 1, 3, and 9 in differing extents of tendon retraction in the torn rotator cuff

Stefan Lakemeier, Juliane Braun, Turgay Efe, Christian Foelsch, Eleni Archontidou-Aprin, Susanne Fuchs-Winkelmann, Juergen R. J. Paletta, Markus D. Schofer

Journal:

Knee Surgery, Sports Traumatology, Arthroscopy

Year:

2011

Language:

english

File:

PDF, 1.67 MB

english, 2011

24

Recent advances in the diagnosis, genetics and treatment of restless legs syndrome

Claudia Trenkwalder, Birgit Högl, Juliane Winkelmann

Journal:

Journal of Neurology

Year:

2009

Language:

english

File:

PDF, 238 KB

english, 2009

25

Parkinson’s disease risk score: moving to a premotor diagnosis

Jürgen Winkler, Reinhard Ehret, Thomas Büttner, Ulrich Dillmann, Wolfgang Fogel, Michael Sabolek, Juliane Winkelmann, Jan Kassubek

Journal:

Journal of Neurology

Year:

2011

Language:

english

File:

PDF, 246 KB

english, 2011

26

Genetics of restless legs syndrome

Juliane Winkelmann

Journal:

Current Neurology and Neuroscience Reports

Year:

2008

Language:

english

File:

PDF, 259 KB

english, 2008

27

Narcolepsy is strongly associated with the T-cell receptor alpha locus

Hallmayer, Joachim, Faraco, Juliette, Lin, Ling, Hesselson, Stephanie, Winkelmann, Juliane, Kawashima, Minae, Mayer, Geert, Plazzi, Giuseppe, Nevsimalova, Sona, Bourgin, Patrice

Journal:

Nature Genetics

Year:

2009

Language:

english

File:

PDF, 244 KB

english, 2009

28

Erratum: Narcolepsy is strongly associated with the T-cell receptor alpha locus

Hallmayer, Joachim, Faraco, Juliette, Lin, Ling, Hesselson, Stephanie, Winkelmann, Juliane, Kawashima, Minae, Mayer, Geert, Plazzi, Giuseppe, Nevsimalova, Sona, Bourgin, Patrice

Journal:

Nature Genetics

Year:

2009

Language:

english

File:

PDF, 55 KB

english, 2009

29

Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions

Fulda, Stephany, Pütz, Benno, Eckstein, Gertrud, Hauk, Stephanie, Winkelmann, Juliane, Schormair, Barbara, Lichtner, Peter, Ripke, Stephan, Xiong, Lan, Jalilzadeh, Shapour

Journal:

Nature Genetics

Year:

2007

Language:

english

File:

PDF, 526 KB

english, 2007

30

10.1038/ng709

Zimprich, Alexander, Grabowski, Monika, Asmus, Friedrich, Naumann, Markus, Berg, Daniela, Bertram, Markus, Scheidtmann, Karl, Kern, Peter, Winkelmann, Juliane, Müller-Myhsok, Bertram, Riedel, Leonhard

Journal:

Nature Genetics

Year:

2001

Language:

english

File:

PDF, 530 KB

english, 2001

31

PSEA: Phenotype Set Enrichment Analysis—A New Method for Analysis of Multiple Phenotypes

Janina S. Ried, Angela Döring, Konrad Oexle, Christa Meisinger, Juliane Winkelmann, Norman Klopp, Thomas Meitinger, Annette Peters, Karsten Suhre, H.-Erich Wichmann, Christian Gieger

Journal:

Genetic Epidemiology

Year:

2012

Language:

english

File:

PDF, 584 KB

english, 2012

32

High-dose treatment with pergolide in Parkinson's disease patients with motor fluctuations and dyskinesias

Alexander Storch, Claudia Trenkwalder, Christian Oehlwein, Juliane Winkelmann, Ulrich Polzer, Hans-Peter Hundemer, Johannes Schwarz

Journal:

Parkinsonism & Related Disorders

Year:

2005

Language:

english

File:

PDF, 104 KB

english, 2005

33

Paroxetine treatment improves motor symptoms in patients with multiple system atrophy

Elisabeth Friess, Tania Kuempfel, Sieglinde Modell, Juliane Winkelmann, Florian Holsboer, Marcus Ising, Claudia Trenkwalder

Journal:

Parkinsonism & Related Disorders

Year:

2006

Language:

english

File:

PDF, 125 KB

english, 2006

34

Mutational screening of THAP1 in a German population with primary dystonia

Maria Kaffe, Nadine Gross, Florian Castrop, Christian Dresel, Christian Gieger, Peter Lichtner, Bernhard Haslinger, Juliane Winkelmann

Journal:

Parkinsonism & Related Disorders

Year:

2012

Language:

english

File:

PDF, 109 KB

english, 2012

35

Diagnostic Standards for Dopaminergic Augmentation of Restless Legs Syndrome: Report from a World Association of Sleep Medicine – International Restless Legs Syndrome Study Group Consensus Conference at the Max Planck Institute

Diego García-Borreguero, Richard P. Allen, Ralf Kohnen, Birgit Högl, Claudia Trenkwalder, Wolfgang Oertel, Wayne A. Hening, Walter Paulus, David Rye, Arthur Walters, Juliane Winkelmann

Journal:

Year:

2007

Language:

english

File:

PDF, 190 KB

english, 2007

36

Erratum to “Diagnostic standards for dopaminergic augmentation of restless legs syndrome: Report from a World Association of Sleep Medicine – International Restless Legs Syndrome Study Group consensus conference at the Max Planck Institute” [Sleep Med. 8 (2007) 520–530]

Diego García-Borreguero, Richard P. Allen, Ralf Kohnen, Birgit Högl, Claudia Trenkwalder, Wolfgang Oertel, Wayne A. Hening, Walter Paulus, David Rye, Arthur Walters, Juliane Winkelmann, Christopher J.

Journal:

Year:

2007

Language:

english

File:

PDF, 52 KB

english, 2007

37

Epidemiology of restless legs syndrome: The current status

Diego Garcia-Borreguero, Renata Egatz, Juliane Winkelmann, Klaus Berger

Journal:

Sleep Medicine Reviews

Year:

2006

Language:

english

File:

PDF, 174 KB

english, 2006

38

Genetics of restless legs syndrome

Juliane Winkelmann, Luigi Ferini-Strambi

Journal:

Sleep Medicine Reviews

Year:

2006

Language:

english

File:

PDF, 98 KB

english, 2006

39

Sleep and periodic limb movements in corticobasal degeneration

Thomas C Wetter, Hans Brunner, Victor Collado-Seidel, Claudia Trenkwalder, Juliane Winkelmann

Journal:

Year:

2002

Language:

english

File:

PDF, 111 KB

english, 2002

40

Opioid and dopamine antagonist drug challenges in untreated restless legs syndrome patients

Juliane Winkelmann, Jan Schadrack, Thomas C Wetter, Walter Zieglgänsberger, Claudia Trenkwalder

Journal:

Year:

2001

Language:

english

File:

PDF, 106 KB

english, 2001

41

Pergolide restores sleep maintenance but impairs sleep EEG synchronization in patients with restless legs syndrome

Hirokuni Tagaya, Thomas C Wetter, Juliane Winkelmann, Marina Rubin, Hans-Peter Hundemer, Claudia Trenkwalder, Elisabeth Friess

Journal:

Year:

2002

Language:

english

File:

PDF, 160 KB

english, 2002

42

Heritability of Sleep Electroencephalogram

Urte Ambrosius, Sonja Lietzenmaier, Renate Wehrle, Adam Wichniak, Stefanie Kalus, Juliane Winkelmann, Thomas Bettecken, Florian Holsboer, Alexander Yassouridis, Elisabeth Friess

Journal:

Biological Psychiatry

Year:

2008

Language:

english

File:

PDF, 265 KB

english, 2008

43

Assessment of spontaneously occurring periodic limb movements in sleep in the rat

Paul Christian Baier, Juliane Winkelmann, Arnold Höhne, Marike Lancel, Claudia Trenkwalder

Journal:

Journal of the Neurological Sciences

Year:

2002

Language:

english

File:

PDF, 157 KB

english, 2002

44

Network-based SNP meta-analysis identifies joint and disjoint genetic features across common human diseases

Arnold, Matthias, Hartsperger, Mara L, Baurecht, Hansjörg, Rodríguez, Elke, Wachinger, Benedikt, Franke, Andre, Kabesch, Michael, Winkelmann, Juliane, Pfeufer, Arne, Romanos, Marcel, Illig, Thomas, Me

Journal:

Year:

2012

Language:

english

File:

PDF, 2.11 MB

english, 2012

45

Mitochondrial membrane protein associated neurodegenration: A novel variant of neurodegeneration with brain iron accumulation

Schulte, Eva C., Claussen, Malte C., Jochim, Angela, Haack, Tobias, Hartig, Monika, Hempel, Maja, Prokisch, Holger, Haun-Jünger, Ursula, Winkelmann, Juliane, Hemmer, Bernhard, Förschler, Annette, Ilg,

Journal:

Movement Disorders

Year:

2013

Language:

english

File:

PDF, 1.03 MB

english, 2013

46

Aetiology and Treatment of Restless Legs Syndrome

Collado-Seidel, Victor, Winkelmann, Juliane, Trenkwalder, Claudia

Journal:

Year:

1999

Language:

english

File:

PDF, 191 KB

english, 1999

47

When restless legs syndrome turns malignant

Schulte, Eva C., Gross, Nadine, Slawik, Helen, Winkelmann, Juliane

Journal:

Year:

2013

Language:

english

File:

PDF, 170 KB

english, 2013

48

Genetics of Restless Legs Syndrome: Mendelian, Complex, and Everything in Between

Schormair, Barbara, Winkelmann, Juliane

Journal:

Sleep Medicine Clinics

Year:

2011

Language:

english

File:

PDF, 265 KB

english, 2011

49

“Malignant restless legs syndrome”—A curse or a blessing?

Schulte, Eva C., Gross, Nadine, Slawik, Helen, Winkelmann, Juliane

Journal:

Year:

2014

Language:

english

File:

PDF, 152 KB

english, 2014

50

Current treatment options for restless legs syndrome

Wetter, Thomas C, Winkelmann, Juliane, Eisensehr, Ilonka

Journal:

Expert Opinion on Pharmacotherapy

Year:

2003

Language:

english

File:

PDF, 182 KB

english, 2003